CMap Candidate Details
Structure:
| CMap ID: | C04899 |
| Pert ID: | BRD-K21295289 |
| Compound Name: | senicapoc |
| Targets: | KCNN4 |
| MoA: | intermediate conductance potassium channel blocker |
| SMILES: | NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120907 | BRD-K21295289 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.85 | 0.2 |
| 120945 | BRD-K21295289 | HEK293 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121014 | BRD-K21295289 | HT29 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121037 | BRD-K21295289 | MCF??7.00 | 0.04 uM | 24 h | 0.19 | 0.79 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121072 | BRD-K21295289 | PC3 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.96 | 0.44 |
| 121103 | BRD-K21295289 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.54 |
| 129095 | BRD-K21295289 | A375 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129112 | BRD-K21295289 | A549 | 2.22 uM | 24 h | 0.25 | 1.06 | 0.18 | -0.2 | -0.69 | 0.02 |
| 129161 | BRD-K21295289 | HELA | 2.22 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |