CMap Candidate Details
Structure:
| CMap ID: | C04909 |
| Pert ID: | BRD-K82036761 |
| Compound Name: | sertraline |
| Targets: | SLC6A3|SLC6A4 |
| MoA: | selective serotonin reuptake inhibitor (SSRI) |
| SMILES: | CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1467 | BRD-K82036761 | NPC | 6.66 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5367 | BRD-K82036761 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5804 | BRD-K82036761 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.14 | 0.86 |
| 5958 | BRD-K82036761 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6057 | BRD-K82036761 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6219 | BRD-K82036761 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6593 | BRD-K82036761 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.04 | 0.54 |
| 25046 | BRD-K82036761 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.2 | 1.07 |
| 37192 | BRD-K82036761 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37311 | BRD-K82036761 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 37746 | BRD-K82036761 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.73 | 0.05 |