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CMap Candidate Details

Structure:
CMap ID: C04915
Pert ID: BRD-K15601958
Compound Name: SEW-2871
Targets: S1PR1
MoA: lysophospholipid receptor agonist
SMILES: FC(F)(F)c1sc(cc1-c1ccccc1)-c1nc(no1)-c1cccc(c1)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4070 BRD-K15601958 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4377 BRD-K15601958 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
4653 BRD-K15601958 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4902 BRD-K15601958 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44319 BRD-K15601958 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44533 BRD-K15601958 A549 10 uM 24 h -0.29 -1.22 0.62 0.0 0.0 0.0
44874 BRD-K15601958 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45178 BRD-K15601958 HEPG2 10 uM 6 h -0.22 -0.92 0.06 -0.28 -0.95 0.39
45446 BRD-K15601958 HT29 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
45782 BRD-K15601958 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45991 BRD-K15601958 NPC 10 uM 24 h -0.22 -0.9 0.04 -0.41 -1.38 2.02
46309 BRD-K15601958 PHH 10 uM 24 h 0.24 0.98 0.09 -0.27 -0.92 0.33
46624 BRD-K15601958 SKB 10 uM 24 h 0.0 0.0 0.0 -0.18 -0.62 0.0
100136 BRD-K15601958 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).