CMap Candidate Details
Structure:
| CMap ID: | C04917 |
| Pert ID: | BRD-K24821794 |
| Compound Name: | SGC-CBP30 |
| Targets: | CREBBP|EP300 |
| MoA: | bromodomain inhibitor |
| SMILES: | COc1ccc(CCc2nc3cc(ccc3n2C[C@H](C)N2CCOCC2)-c2c(C)noc2C)cc1Cl |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90833 | BRD-K24821794 | MCF10A | 10 uM | 24 h | -0.26 | -1.08 | 0.31 | -0.34 | -1.13 | 1.01 |
| 96757 | BRD-K24821794 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118687 | BRD-K24821794 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.98 | 0.36 |
| 118720 | BRD-K24821794 | A549 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118757 | BRD-K24821794 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118796 | BRD-K24821794 | HCC515 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 118838 | BRD-K24821794 | HEPG2 | 10 uM | 24 h | -0.27 | -1.11 | 0.38 | 0.0 | 0.0 | 0.0 |
| 118880 | BRD-K24821794 | HT29 | 10 uM | 24 h | -0.31 | -1.29 | 0.77 | -0.24 | -0.81 | 0.14 |
| 118921 | BRD-K24821794 | MCF??7.00 | 10 uM | 24 h | -0.25 | -1.04 | 0.21 | 0.0 | 0.0 | 0.0 |