CMap Candidate Details
Structure:
| CMap ID: | C04943 |
| Pert ID: | BRD-K51333959 |
| Compound Name: | siramesine |
| Targets: | ADRA1A|ADRA1B|ADRA1D |
| MoA: | sigma receptor antagonist |
| SMILES: | Fc1ccc(cc1)-n1cc(CCCCN2CCC3(CC2)OCc2ccccc32)c2ccccc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121559 | BRD-K51333959 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.07 | 0.64 |
| 121598 | BRD-K51333959 | HA1E | 10 uM | 24 h | 0.2 | 0.82 | 0.0 | 0.41 | 1.44 | 2.21 |
| 121636 | BRD-K51333959 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.38 | 1.33 | 1.72 |
| 121660 | BRD-K51333959 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121679 | BRD-K51333959 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.85 | 0.2 |
| 121703 | BRD-K51333959 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.13 | 0.85 |
| 129689 | BRD-K51333959 | PC3 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |