CMap Candidate Details
Structure:
| CMap ID: | C04956 |
| Pert ID: | BRD-A47364545 |
| Compound Name: | SK&F-10047-(+) |
| Targets: | SIGMAR1 |
| MoA: | sigma receptor agonist |
| SMILES: | C[C@H]1C2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96395 | BRD-A47364545 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125279 | BRD-A47364545 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.24 | 1.35 |
| 125311 | BRD-A47364545 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 125444 | BRD-A47364545 | MCF??7.00 | 3.33 uM | 24 h | -0.22 | -0.91 | 0.05 | -0.25 | -0.83 | 0.16 |
| 125472 | BRD-A47364545 | MDAMB231 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.88 | 0.24 |
| 133338 | BRD-A47364545 | A375 | 2.22 uM | 24 h | -0.21 | -0.86 | 0.01 | -0.31 | -1.06 | 0.73 |
| 133362 | BRD-A47364545 | A549 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133420 | BRD-A47364545 | HELA | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133453 | BRD-A47364545 | HT29 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133482 | BRD-A47364545 | JURKAT | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 133516 | BRD-A47364545 | MCF10A | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.21 | 1.24 |
| 133605 | BRD-A47364545 | THP1 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.2 | 0.71 | 0.02 |
| 133631 | BRD-A47364545 | YAPC | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.4 | 1.43 | 2.2 |