CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04966
Pert ID:	BRD-A72703248
Compound Name:	SKF-96365
Targets:	CYP3A4\|PKD2\|TRPC1\|TRPC3\|TRPC4\|TRPC5\|TRPV2
MoA:	calcium channel blocker
SMILES:	COc1ccc(CCCOC(Cn2ccnc2)c2ccc(OC)cc2)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5410	BRD-A72703248	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5545	BRD-A72703248	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5990	BRD-A72703248	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6392	BRD-A72703248	VCAP	10 uM	24 h	0.24	0.98	0.09	-0.23	-0.77	0.08
44491	BRD-A72703248	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44785	BRD-A72703248	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45105	BRD-A72703248	HEPG2	10 uM	6 h	0.22	0.9	0.02	0.28	0.98	0.36
45905	BRD-A72703248	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46221	BRD-A72703248	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46536	BRD-A72703248	SKB	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.88	0.25
96979	BRD-A72703248	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
97058	BRD-A72703248	PC3	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.17	1.12
97802	BRD-A72703248	MCF??7.00	10 uM	24 h	0.22	0.93	0.05	0.0	0.0	0.0
100312	BRD-A72703248	U2OS	12.5 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary