CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05004
Pert ID:	BRD-K84798689
Compound Name:	sodium-tanshinone-ii-a-sulfonate
Targets:
MoA:	potassium channel activator
SMILES:	Cc1c2c(oc1S(O)(=O)=O)-c1ccc3c(CCCC3(C)C)c1C(=O)C2=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125968	BRD-K84798689	A375	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126036	BRD-K84798689	HELA	1.11 uM	24 h	0.0	0.0	0.0	-0.26	-0.87	0.24
126096	BRD-K84798689	HUVEC	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126144	BRD-K84798689	JURKAT	1.11 uM	24 h	-0.27	-1.12	0.38	-0.29	-0.96	0.43
126197	BRD-K84798689	MCF10A	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.89	0.26
126243	BRD-K84798689	MDAMB231	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126315	BRD-K84798689	THP1	0.04 uM	24 h	0.23	0.95	0.06	-0.36	-1.21	1.24
126346	BRD-K84798689	YAPC	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134047	BRD-K84798689	A549	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134074	BRD-K84798689	HA1E	0.01 uM	24 h	0.0	0.0	0.0	0.23	0.82	0.1
134118	BRD-K84798689	HEK293	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134191	BRD-K84798689	HT29	2.22 uM	24 h	0.0	0.0	0.0	0.27	0.95	0.31
134238	BRD-K84798689	MCF??7.00	0.08 uM	24 h	0.0	0.0	0.0	-0.38	-1.28	1.45
134295	BRD-K84798689	PC3	0.74 uM	24 h	0.0	0.0	0.0	0.2	0.7	0.02

Summary