CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05006
Pert ID:	BRD-K01039503
Compound Name:	sofalcone
Targets:	CBR1
MoA:	mucus protecting agent
SMILES:	CC(C)=CCOc1ccc(\C=C\C(=O)c2ccc(OCC=C(C)C)cc2OCC(O)=O)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
122831	BRD-K01039503	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122858	BRD-K01039503	HA1E	10 uM	24 h	0.22	0.92	0.04	-0.36	-1.21	1.24
122889	BRD-K01039503	HEK293	0.125 uM	24 h	0.0	0.0	0.0	0.26	0.91	0.23
122937	BRD-K01039503	HELA	10 uM	24 h	-0.3	-1.26	0.71	0.0	0.0	0.0
122969	BRD-K01039503	HT29	10 uM	24 h	0.0	0.0	0.0	0.29	1.02	0.48
123014	BRD-K01039503	JURKAT	3.33 uM	24 h	-0.2	-0.83	0.0	0.0	0.0	0.0
123060	BRD-K01039503	MCF10A	10 uM	24 h	0.3	1.24	0.52	0.26	0.94	0.28
123074	BRD-K01039503	MCF??7.00	10 uM	24 h	0.23	0.97	0.08	-0.3	-1.01	0.56
123103	BRD-K01039503	MDAMB231	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123145	BRD-K01039503	PC3	10 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.35
123175	BRD-K01039503	THP1	0.37 uM	24 h	-0.25	-1.04	0.22	-0.39	-1.3	1.58
131240	BRD-K01039503	A549	0.25 uM	24 h	-0.27	-1.12	0.39	-0.27	-0.9	0.28
131351	BRD-K01039503	HUVEC	0.08 uM	24 h	0.22	0.92	0.04	-0.31	-1.03	0.62
131490	BRD-K01039503	YAPC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary