CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05013
Pert ID:	BRD-K14681867
Compound Name:	somatostatin
Targets:	OPRD1\|OPRM1\|SSTR1\|SSTR2\|SSTR3\|SSTR4\|SSTR5
MoA:	somatostatin receptor agonist
SMILES:	C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
33670	BRD-K14681867	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
34051	BRD-K14681867	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
34320	BRD-K14681867	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35100	BRD-K14681867	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35298	BRD-K14681867	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
35544	BRD-K14681867	NEU	10 uM	24 h	0.2	0.83	0.0	-0.44	-1.47	15.35
35736	BRD-K14681867	NPC	10 uM	24 h	0.29	1.2	0.42	-0.22	-0.74	0.05
35937	BRD-K14681867	PC3	10 uM	24 h	-0.18	-0.77	0.0	-0.29	-0.97	0.45
36209	BRD-K14681867	PHH	10 uM	24 h	0.0	0.0	0.0	-0.44	-1.47	15.35
36504	BRD-K14681867	SKB	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.19	1.16
36781	BRD-K14681867	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.86	0.22
96116	BRD-K14681867	A549	10 uM	24 h	-0.29	-1.21	0.57	0.0	0.0	0.0

Summary