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CMap Candidate Details

Structure:
CMap ID: C05036
Pert ID: BRD-K55468218
Compound Name: spiperone
Targets: ADRA1A|ADRA1B|ADRA1D|DRD1|DRD2|DRD3|DRD4|DRD5|HTR1A|HTR1D|HTR2A|HTR2B|HTR2C|HTR6|HTR7
MoA: dopamine receptor antagonist
SMILES: Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5468 BRD-K55468218 HA1E 10 uM 6 h 0.0 0.0 0.0 0.26 0.93 0.27
5791 BRD-K55468218 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.89
6204 BRD-K55468218 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6571 BRD-K55468218 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39146 BRD-K55468218 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39462 BRD-K55468218 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39717 BRD-K55468218 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40292 BRD-K55468218 HT29 10 uM 6 h 0.0 0.0 0.0 -0.16 -0.55 0.0
40483 BRD-K55468218 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40830 BRD-K55468218 NEU 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
41473 BRD-K55468218 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53461 BRD-K55468218 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.4 2.02
53594 BRD-K55468218 HUH7 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.41
53737 BRD-K55468218 PHH 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98701 BRD-K55468218 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99670 BRD-K55468218 U2OS 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.34
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).