CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05041
Pert ID:	BRD-A72483914
Compound Name:	spiroxatrine
Targets:	ADRA1A\|ADRA1B\|ADRA1D\|ADRA2A\|ADRA2B\|ADRA2C\|HTR1A\|HTR2B
MoA:	serotonin receptor antagonist
SMILES:	O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
6687	BRD-A72483914	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7110	BRD-A72483914	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
7411	BRD-A72483914	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
7969	BRD-A72483914	HT29	10 uM	6 h	-0.27	-1.14	0.42	-0.25	-0.85	0.19
8137	BRD-A72483914	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
8330	BRD-A72483914	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
8778	BRD-A72483914	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
91021	BRD-A72483914	HUH7	8 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
100310	BRD-A72483914	U2OS	10 uM	6 h	0.0	0.0	0.0	0.21	0.76	0.05

Summary