CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05053
Pert ID:	BRD-K62562723
Compound Name:	SR-2640
Targets:	CYSLTR1
MoA:	leukotriene receptor antagonist
SMILES:	OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
99311	BRD-K62562723	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
124932	BRD-K62562723	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124992	BRD-K62562723	HA1E	10 uM	24 h	0.19	0.81	0.0	0.0	0.0	0.0
125094	BRD-K62562723	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.01	0.56
125104	BRD-K62562723	MDAMB231	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.88
125130	BRD-K62562723	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125151	BRD-K62562723	THP1	10 uM	24 h	0.0	0.0	0.0	0.32	1.13	0.84
125200	BRD-K62562723	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132992	BRD-K62562723	A549	2.22 uM	24 h	0.0	0.0	0.0	-0.22	-0.73	0.05
133037	BRD-K62562723	HEK293	2.22 uM	24 h	-0.25	-1.05	0.23	0.0	0.0	0.0
133085	BRD-K62562723	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133109	BRD-K62562723	HT29	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133144	BRD-K62562723	JURKAT	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133191	BRD-K62562723	MCF10A	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary