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CMap Candidate Details

Structure:
CMap ID: C05056
Pert ID: BRD-K43002771
Compound Name: SR-33805
Targets:
MoA: calcium channel blocker
SMILES: COc1ccc(CCN(C)CCCOc2ccc(cc2)S(=O)(=O)c2c(C(C)C)c3ccccc3n2C)cc1OC
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123246 BRD-K43002771 A375 3.33 uM 24 h -0.3 -1.24 0.65 0.0 0.0 0.0
123266 BRD-K43002771 A549 10 uM 24 h 0.0 0.0 0.0 0.4 1.42 2.2
123279 BRD-K43002771 HA1E 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
123293 BRD-K43002771 HEK293 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
123320 BRD-K43002771 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123353 BRD-K43002771 HT29 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.62
123373 BRD-K43002771 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123382 BRD-K43002771 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.46 15.35
123404 BRD-K43002771 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123433 BRD-K43002771 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123470 BRD-K43002771 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123503 BRD-K43002771 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131740 BRD-K43002771 HUVEC 0.25 uM 24 h -0.28 -1.15 0.44 0.0 0.0 0.0
131794 BRD-K43002771 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).