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CMap Candidate Details

Structure:
CMap ID: C00506
Pert ID: BRD-K03406345
Compound Name: azacitidine
Targets: DNMT1|DNMT3A
MoA: DNA methyltransferase inhibitor
SMILES: Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49797 BRD-K03406345 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50492 BRD-K03406345 HT29 10 uM 6 h 0.2 0.82 0.0 0.0 0.0 0.0
50648 BRD-K03406345 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
50901 BRD-K03406345 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51117 BRD-K03406345 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53285 BRD-K03406345 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93614 BRD-K03406345 A549 10 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
93650 BRD-K03406345 ASC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93710 BRD-K03406345 CD34 10 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
93756 BRD-K03406345 HA1E 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93790 BRD-K03406345 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93837 BRD-K03406345 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93883 BRD-K03406345 HELA 3.33 uM 24 h 0.3 1.23 0.5 0.0 0.0 0.0
93923 BRD-K03406345 HEPG2 10 uM 24 h 0.2 0.83 0.0 0.0 0.0 0.0
93958 BRD-K03406345 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94021 BRD-K03406345 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
94101 BRD-K03406345 NEU 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94174 BRD-K03406345 NPC 3.33 uM 24 h 0.2 0.83 0.0 0.0 0.0 0.0
94285 BRD-K03406345 SKL 10 uM 24 h 0.25 1.03 0.14 -0.31 -1.03 0.63
94334 BRD-K03406345 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94378 BRD-K03406345 YAPC 1.11 uM 24 h 0.16 0.66 0.0 -0.3 -1.01 0.57
136405 BRD-K03406345 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).