CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05071
Pert ID:	BRD-K41783120
Compound Name:	STA-5326
Targets:	IL12A
MoA:	interleukin synthesis inhibitor
SMILES:	Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
123262	BRD-K41783120	A549	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123316	BRD-K41783120	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123346	BRD-K41783120	HT29	0.37 uM	24 h	-0.14	-0.6	0.0	0.0	0.0	0.0
123368	BRD-K41783120	MCF10A	3.33 uM	24 h	0.0	0.0	0.0	0.27	0.95	0.32
123399	BRD-K41783120	MDAMB231	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123426	BRD-K41783120	PC3	10 uM	24 h	0.0	0.0	0.0	0.38	1.34	1.72
123464	BRD-K41783120	THP1	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131531	BRD-K41783120	A375	2.22 uM	24 h	0.16	0.68	0.0	0.3	1.08	0.64
131593	BRD-K41783120	HA1E	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131634	BRD-K41783120	HEK293	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131732	BRD-K41783120	HUVEC	2.22 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.36
131786	BRD-K41783120	JURKAT	2.22 uM	24 h	0.21	0.87	0.01	0.41	1.45	2.22
131863	BRD-K41783120	MCF??7.00	0.74 uM	24 h	-0.19	-0.78	0.0	0.34	1.22	1.15
131958	BRD-K41783120	YAPC	2.22 uM	24 h	0.0	0.0	0.0	0.36	1.29	1.42

Summary