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CMap Candidate Details

Structure:
CMap ID: C05092
Pert ID: BRD-K20287671
Compound Name: SU-4312
Targets: KDR|PDGFRB
MoA: PDGFR tyrosine kinase receptor inhibitor; tyrosine kinase inhibitor; VEGFR inhibitor
SMILES: CN(C)c1ccc(cc1)\C=C1/C(=O)Nc2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2995 BRD-K20287671 HA1E 10 uM 6 h -0.21 -0.88 0.03 0.0 0.0 0.0
3158 BRD-K20287671 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3473 BRD-K20287671 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3745 BRD-K20287671 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
41742 BRD-K20287671 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42077 BRD-K20287671 A549 10 uM 6 h 0.28 1.15 0.33 0.0 0.0 0.0
42323 BRD-K20287671 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42652 BRD-K20287671 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42956 BRD-K20287671 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43168 BRD-K20287671 MCF??7.00 10 uM 24 h 0.2 0.84 0.0 -0.34 -1.14 1.02
43514 BRD-K20287671 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).