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CMap Candidate Details

Structure:
CMap ID: C05114
Pert ID: BRD-K50859149
Compound Name: sulfafurazole
Targets:
MoA: bacterial antifolate
SMILES: Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3376 BRD-K50859149 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3823 BRD-K50859149 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44982 BRD-K50859149 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45831 BRD-K50859149 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46098 BRD-K50859149 NPC 10 uM 24 h -0.23 -0.96 0.1 -0.38 -1.27 1.39
46413 BRD-K50859149 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46737 BRD-K50859149 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51477 BRD-K50859149 PC3 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.85
52808 BRD-K50859149 HEPG2 2.5 uM 24 h 0.26 1.07 0.19 0.0 0.0 0.0
99623 BRD-K50859149 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124591 BRD-K50859149 A549 3.33 uM 24 h -0.28 -1.15 0.44 0.0 0.0 0.0
124647 BRD-K50859149 HELA 0.125 uM 24 h 0.2 0.85 0.01 0.24 0.87 0.17
124677 BRD-K50859149 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124776 BRD-K50859149 MDAMB231 1.11 uM 24 h -0.29 -1.2 0.57 -0.29 -0.99 0.5
124867 BRD-K50859149 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132655 BRD-K50859149 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132711 BRD-K50859149 HA1E 0.03 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
132736 BRD-K50859149 HEK293 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132822 BRD-K50859149 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132853 BRD-K50859149 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132940 BRD-K50859149 YAPC 0.25 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).