CMap Candidate Details
Structure:
| CMap ID: | C05131 |
| Pert ID: | BRD-K10670311 |
| Compound Name: | sulfasalazine |
| Targets: | ACAT1|ALOX5|CHUK|IKBKB|PLA2G1B|PPARG|PTGS1|PTGS2|SLC46A1|SLC7A11|TBXAS1 |
| MoA: | cyclooxygenase inhibitor |
| SMILES: | OC(=O)c1cc(ccc1O)\N=N\c1ccc(cc1)S(=O)(=O)Nc1ccccn1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24554 | BRD-K10670311 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25490 | BRD-K10670311 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91488 | BRD-K10670311 | HUH7 | 8 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 100068 | BRD-K10670311 | U2OS | 10 uM | 6 h | -0.26 | -1.06 | 0.26 | 0.0 | 0.0 | 0.0 |
| 121160 | BRD-K10670311 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121230 | BRD-K10670311 | HA1E | 0.125 uM | 24 h | -0.24 | -0.98 | 0.12 | 0.0 | 0.0 | 0.0 |
| 121271 | BRD-K10670311 | HELA | 0.125 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121292 | BRD-K10670311 | MCF??7.00 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121353 | BRD-K10670311 | YAPC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.29 | 1.03 | 0.51 |
| 129309 | BRD-K10670311 | HT29 | 2.22 uM | 24 h | 0.28 | 1.18 | 0.39 | 0.0 | 0.0 | 0.0 |
| 129357 | BRD-K10670311 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.99 | 0.42 |