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CMap Candidate Details

Structure:
CMap ID: C05158
Pert ID: BRD-K15170068
Compound Name: swainsonine
Targets: MAN2A1
MoA: alpha mannosidase inhibitor
SMILES: O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122269 BRD-K15170068 A375 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122373 BRD-K15170068 MCF10A 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122399 BRD-K15170068 MCF??7.00 0.05 uM 24 h 0.21 0.88 0.01 0.27 0.97 0.35
122492 BRD-K15170068 THP1 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130569 BRD-K15170068 A549 0.3 uM 24 h -0.19 -0.78 0.0 -0.31 -1.05 0.71
130601 BRD-K15170068 HA1E 0.03 uM 24 h 0.22 0.94 0.05 0.0 0.0 0.0
130636 BRD-K15170068 HEK293 2.5 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
130679 BRD-K15170068 HELA 2.5 uM 24 h 0.27 1.11 0.25 0.0 0.0 0.0
130721 BRD-K15170068 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130794 BRD-K15170068 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130819 BRD-K15170068 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130845 BRD-K15170068 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).