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CMap Candidate Details

Structure:
CMap ID: C05165
Pert ID: BRD-K02501528
Compound Name: S18986
Targets: GRIA1|GRIA2|GRIA3|GRIA4
MoA: glutamate receptor modulator
SMILES: O=S1(=O)N[C@H]2CCCN2c2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122904 BRD-K02501528 HEK293 10 uM 24 h 0.23 0.95 0.06 -0.23 -0.77 0.08
122980 BRD-K02501528 HT29 3.33 uM 24 h 0.27 1.11 0.25 -0.39 -1.3 1.61
123029 BRD-K02501528 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.39
123119 BRD-K02501528 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
123191 BRD-K02501528 THP1 0.125 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
131215 BRD-K02501528 A375 2.22 uM 24 h 0.17 0.7 0.0 0.0 0.0 0.0
131251 BRD-K02501528 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131284 BRD-K02501528 HA1E 0.74 uM 24 h 0.29 1.22 0.48 -0.34 -1.14 1.03
131310 BRD-K02501528 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131367 BRD-K02501528 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131405 BRD-K02501528 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
131443 BRD-K02501528 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131467 BRD-K02501528 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131504 BRD-K02501528 YAPC 0.08 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).