CMap Candidate Details
Structure:
| CMap ID: | C05168 |
| Pert ID: | BRD-K31843556 |
| Compound Name: | T-0070907 |
| Targets: | PPARG |
| MoA: | PPAR receptor antagonist |
| SMILES: | [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc1ccncc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 3006 | BRD-K31843556 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 3172 | BRD-K31843556 | HCC515 | 10 uM | 24 h | 0.27 | 1.14 | 0.31 | 0.28 | 0.98 | 0.38 |
| 3481 | BRD-K31843556 | PC3 | 10 uM | 24 h | -0.23 | -0.95 | 0.09 | 0.0 | 0.0 | 0.0 |
| 3766 | BRD-K31843556 | VCAP | 10 uM | 24 h | -0.21 | -0.87 | 0.02 | 0.0 | 0.0 | 0.0 |
| 44361 | BRD-K31843556 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 44694 | BRD-K31843556 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.32 |
| 44919 | BRD-K31843556 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.32 | 1.71 |
| 45221 | BRD-K31843556 | HEPG2 | 10 uM | 6 h | 0.28 | 1.18 | 0.39 | 0.31 | 1.1 | 0.68 |
| 45490 | BRD-K31843556 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.1 |
| 45680 | BRD-K31843556 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.08 | 0.65 |
| 46355 | BRD-K31843556 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 46673 | BRD-K31843556 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.76 | 0.07 |
| 99836 | BRD-K31843556 | U2OS | 10 uM | 6 h | -0.2 | -0.83 | 0.0 | -0.38 | -1.28 | 1.45 |