CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05171
Pert ID:	BRD-K84925803
Compound Name:	T-5224
Targets:	JUN
MoA:	AP inhibitor
SMILES:	OC(=O)CCc1cc(ccc1OCc1ccc2c(O)noc2c1)C(=O)c1ccc(OC2CCCC2)cc1O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125563	BRD-K84925803	A375	0.04 uM	24 h	0.0	0.0	0.0	0.25	0.89	0.21
125604	BRD-K84925803	A549	0.125 uM	24 h	0.21	0.87	0.01	-0.35	-1.17	1.14
125637	BRD-K84925803	HEK293	0.37 uM	24 h	0.0	0.0	0.0	-0.27	-0.9	0.28
125712	BRD-K84925803	HUVEC	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125794	BRD-K84925803	MCF10A	0.04 uM	24 h	0.22	0.91	0.04	0.0	0.0	0.0
125819	BRD-K84925803	MCF??7.00	1.11 uM	24 h	0.0	0.0	0.0	-0.35	-1.18	1.14
125865	BRD-K84925803	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125911	BRD-K84925803	YAPC	0.04 uM	24 h	0.2	0.84	0.0	-0.21	-0.71	0.03
133685	BRD-K84925803	HA1E	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133752	BRD-K84925803	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133785	BRD-K84925803	HT29	2.22 uM	24 h	0.31	1.28	0.64	0.0	0.0	0.0
133818	BRD-K84925803	JURKAT	2.22 uM	24 h	-0.17	-0.72	0.0	-0.21	-0.7	0.03
133900	BRD-K84925803	MDAMB231	0.74 uM	24 h	0.0	0.0	0.0	-0.29	-0.99	0.5
133963	BRD-K84925803	THP1	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary