Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C05177
Pert ID: BRD-K52313696
Compound Name: tacedinaline
Targets: HDAC1
MoA: HDAC inhibitor
SMILES: CC(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1444 BRD-K52313696 NPC 0.3 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95382 BRD-K52313696 U2OS 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96000 BRD-K52313696 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97259 BRD-K52313696 HAP1 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99053 BRD-K52313696 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
118425 BRD-K52313696 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118544 BRD-K52313696 HEPG2 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.21
118586 BRD-K52313696 HT29 1.11 uM 24 h -0.2 -0.84 0.0 -0.26 -0.87 0.23
119267 BRD-K52313696 HCC515 10 uM 24 h -0.21 -0.9 0.04 -0.33 -1.12 0.94
119374 BRD-K52313696 PC3 3.33 uM 24 h 0.0 0.0 0.0 -0.2 -0.67 0.01
124407 BRD-K52313696 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132324 BRD-K52313696 A375 0.74 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
132383 BRD-K52313696 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132415 BRD-K52313696 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132440 BRD-K52313696 HELA 2.22 uM 24 h 0.27 1.14 0.31 0.23 0.83 0.11
132487 BRD-K52313696 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132517 BRD-K52313696 MCF??7.00 0.74 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
132545 BRD-K52313696 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132595 BRD-K52313696 THP1 2.22 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
132639 BRD-K52313696 YAPC 2.22 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).