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CMap Candidate Details

Structure:
CMap ID: C05178
Pert ID: BRD-K81473089
Compound Name: tacrine
Targets: ACHE|BCHE
MoA: acetylcholinesterase inhibitor
SMILES: Nc1c2CCCCc2nc2ccccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50416 BRD-K81473089 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51071 BRD-K81473089 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
91003 BRD-K81473089 HUH7 15 uM 72 h 0.0 0.0 0.0 0.25 0.88 0.18
96702 BRD-K81473089 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97178 BRD-K81473089 A375 1.11 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
126047 BRD-K81473089 HT29 10 uM 24 h 0.19 0.81 0.0 -0.31 -1.05 0.72
126116 BRD-K81473089 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126169 BRD-K81473089 MCF10A 0.04 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
126215 BRD-K81473089 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126234 BRD-K81473089 MDAMB231 10 uM 24 h -0.25 -1.03 0.2 0.0 0.0 0.0
126288 BRD-K81473089 THP1 1.11 uM 24 h 0.23 0.98 0.09 -0.23 -0.79 0.1
126334 BRD-K81473089 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134031 BRD-K81473089 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134060 BRD-K81473089 HA1E 0.08 uM 24 h 0.29 1.19 0.42 0.33 1.17 0.94
134090 BRD-K81473089 HEK293 0.08 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
134141 BRD-K81473089 HELA 0.01 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
134203 BRD-K81473089 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).