CMap Candidate Details
Structure:
| CMap ID: | C05181 |
| Pert ID: | BRD-K23728141 |
| Compound Name: | tafamidis-meglumine |
| Targets: | TTR |
| MoA: | transthyretin amyloid inhibitor |
| SMILES: | OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120866 | BRD-K23728141 | A375 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120888 | BRD-K23728141 | A549 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120956 | BRD-K23728141 | HEK293 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121044 | BRD-K23728141 | MCF??7.00 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121078 | BRD-K23728141 | PC3 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121112 | BRD-K23728141 | YAPC | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129136 | BRD-K23728141 | HA1E | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.77 | 0.06 |
| 129164 | BRD-K23728141 | HELA | 0.08 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129191 | BRD-K23728141 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |