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CMap Candidate Details

Structure:
CMap ID: C05204
Pert ID: BRD-A98378129
Compound Name: talniflumate
Targets: CLCA1
MoA: cyclooxygenase inhibitor
SMILES: FC(F)(F)c1cccc(Nc2ncccc2C(=O)OC2OC(=O)c3ccccc23)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1717 BRD-A98378129 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1861 BRD-A98378129 HCC515 10 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
2360 BRD-A98378129 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2568 BRD-A98378129 VCAP 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
42038 BRD-A98378129 A549 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.3 1.59
42253 BRD-A98378129 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42589 BRD-A98378129 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42895 BRD-A98378129 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43279 BRD-A98378129 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43450 BRD-A98378129 NPC 10 uM 24 h -0.19 -0.78 0.0 0.22 0.79 0.07
43756 BRD-A98378129 PHH 10 uM 24 h 0.3 1.23 0.5 0.0 0.0 0.0
44040 BRD-A98378129 SKB 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
99936 BRD-A98378129 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).