CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05216
Pert ID:	BRD-K25186396
Compound Name:	tangeritin
Targets:
MoA:	cell cycle inhibitor
SMILES:	COc1ccc(cc1)-c1cc(=O)c2c(OC)c(OC)c(OC)c(OC)c2o1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
3000	BRD-K25186396	HA1E	10 uM	6 h	0.0	0.0	0.0	0.27	0.97	0.35
3347	BRD-K25186396	HCC515	10 uM	6 h	0.0	0.0	0.0	0.3	1.08	0.65
3478	BRD-K25186396	PC3	10 uM	24 h	0.21	0.87	0.01	-0.3	-1.02	0.62
3756	BRD-K25186396	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44346	BRD-K25186396	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44553	BRD-K25186396	A549	10 uM	24 h	0.0	0.0	0.0	-0.24	-0.8	0.11
44903	BRD-K25186396	ASC	10 uM	24 h	-0.24	-1.02	0.18	-0.2	-0.69	0.02
45207	BRD-K25186396	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45473	BRD-K25186396	HT29	10 uM	6 h	0.0	0.0	0.0	-0.22	-0.75	0.06
45672	BRD-K25186396	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46022	BRD-K25186396	NPC	10 uM	24 h	-0.32	-1.31	0.82	-0.33	-1.12	0.94
46340	BRD-K25186396	PHH	10 uM	24 h	0.24	1.02	0.12	-0.28	-0.94	0.39
46656	BRD-K25186396	SKB	10 uM	24 h	-0.32	-1.34	0.98	0.3	1.07	0.61

Summary