CMap Candidate Details
Structure:
| CMap ID: | C00522 |
| Pert ID: | BRD-K99113996 |
| Compound Name: | AZD2014 |
| Targets: | MTOR |
| MoA: | mTOR inhibitor |
| SMILES: | CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1CCOC[C@@H]1C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 127354 | BRD-K99113996 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.82 | 0.14 |
| 127394 | BRD-K99113996 | A549 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.94 |
| 127426 | BRD-K99113996 | HA1E | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127517 | BRD-K99113996 | JURKAT | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127556 | BRD-K99113996 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.4 | -1.36 | 2.02 |
| 127609 | BRD-K99113996 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.18 | 1.15 |
| 127687 | BRD-K99113996 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135370 | BRD-K99113996 | HELA | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.23 | 1.28 |
| 135404 | BRD-K99113996 | HT29 | 2.22 uM | 24 h | 0.19 | 0.81 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135471 | BRD-K99113996 | MCF??7.00 | 0.25 uM | 24 h | 0.27 | 1.12 | 0.27 | -0.34 | -1.13 | 1.0 |
| 135498 | BRD-K99113996 | THP1 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.16 | 1.11 |