Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C05224
Pert ID: BRD-K59506194
Compound Name: targinine
Targets: NOS3
MoA: nitric oxide synthase inhibitor
SMILES: CNC(=N)NCCC[C@H](N)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123574 BRD-K59506194 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.67 0.02
123691 BRD-K59506194 MCF10A 0.04 uM 24 h -0.22 -0.92 0.06 -0.29 -0.98 0.48
131982 BRD-K59506194 A375 2.22 uM 24 h 0.21 0.86 0.01 0.24 0.85 0.15
132012 BRD-K59506194 HA1E 0.03 uM 24 h 0.3 1.24 0.52 0.0 0.0 0.0
132037 BRD-K59506194 HELA 0.08 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.42
132059 BRD-K59506194 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132082 BRD-K59506194 MCF??7.00 0.08 uM 24 h 0.34 1.42 1.07 -0.37 -1.26 1.35
132114 BRD-K59506194 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132139 BRD-K59506194 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.75
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).