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CMap Candidate Details

Structure:
CMap ID: C05228
Pert ID: BRD-K44844162
Compound Name: taselisib
Targets: PIK3CA
MoA: PI3K inhibitor
SMILES: CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)-c1cnn(c1)C(C)(C)C(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1298 BRD-K44844162 MCF??7.00 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
87327 BRD-K44844162 BJAB 10 uM 6 h 0.0 0.0 0.0 0.23 0.82 0.1
87358 BRD-K44844162 HBL1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87408 BRD-K44844162 K562 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87456 BRD-K44844162 KMS34 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87503 BRD-K44844162 MINO 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
87560 BRD-K44844162 NALM6 0.66 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
87610 BRD-K44844162 OCILY10 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87661 BRD-K44844162 OCILY19 2.5 uM 24 h 0.18 0.76 0.0 0.0 0.0 0.0
87712 BRD-K44844162 OCILY3 10 uM 24 h 0.35 1.44 1.12 -0.25 -0.84 0.17
87759 BRD-K44844162 SKMEL5 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87834 BRD-K44844162 TMD8 2.5 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.31
95436 BRD-K44844162 U2OS 10 uM 48 h 0.0 0.0 0.0 -0.4 -1.34 1.85
125228 BRD-K44844162 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125251 BRD-K44844162 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125288 BRD-K44844162 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
125343 BRD-K44844162 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125385 BRD-K44844162 JURKAT 10 uM 24 h -0.22 -0.9 0.05 0.0 0.0 0.0
125411 BRD-K44844162 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125536 BRD-K44844162 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133377 BRD-K44844162 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133441 BRD-K44844162 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
133535 BRD-K44844162 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133575 BRD-K44844162 PC3 2.22 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
133592 BRD-K44844162 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).