CMap Candidate Details
Structure:
| CMap ID: | C05230 |
| Pert ID: | BRD-K42495768 |
| Compound Name: | tasisulam |
| Targets: | |
| MoA: | apoptosis stimulant |
| SMILES: | Clc1ccc(C(=O)NS(=O)(=O)c2ccc(Br)s2)c(Cl)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123240 | BRD-K42495768 | A375 | 10 uM | 24 h | 0.24 | 1.0 | 0.11 | -0.28 | -0.94 | 0.37 |
| 123264 | BRD-K42495768 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123348 | BRD-K42495768 | HT29 | 10 uM | 24 h | 0.24 | 0.99 | 0.1 | -0.28 | -0.93 | 0.34 |
| 123370 | BRD-K42495768 | MCF10A | 10 uM | 24 h | -0.23 | -0.96 | 0.1 | -0.26 | -0.89 | 0.26 |
| 123381 | BRD-K42495768 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123400 | BRD-K42495768 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123428 | BRD-K42495768 | PC3 | 3.33 uM | 24 h | 0.3 | 1.23 | 0.5 | -0.36 | -1.22 | 1.24 |
| 123465 | BRD-K42495768 | THP1 | 10 uM | 24 h | 0.23 | 0.97 | 0.08 | 0.0 | 0.0 | 0.0 |
| 131595 | BRD-K42495768 | HA1E | 2.22 uM | 24 h | 0.23 | 0.94 | 0.06 | -0.22 | -0.73 | 0.05 |
| 131636 | BRD-K42495768 | HEK293 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131666 | BRD-K42495768 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.2 | 0.72 | 0.03 |
| 131734 | BRD-K42495768 | HUVEC | 0.74 uM | 24 h | -0.25 | -1.05 | 0.24 | 0.0 | 0.0 | 0.0 |
| 131788 | BRD-K42495768 | JURKAT | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131960 | BRD-K42495768 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.02 |