CMap Candidate Details
Structure:
| CMap ID: | C05240 |
| Pert ID: | BRD-A18611368 |
| Compound Name: | tazobactam |
| Targets: | |
| MoA: | beta lactamase inhibitor |
| SMILES: | C[C@]1(Cn2ccnn2)C(N2C(CC2=O)S1(=O)=O)C(O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120852 | BRD-A18611368 | A375 | 0.125 uM | 24 h | -0.26 | -1.1 | 0.34 | 0.0 | 0.0 | 0.0 |
| 120880 | BRD-A18611368 | A549 | 10 uM | 24 h | -0.31 | -1.3 | 0.81 | -0.36 | -1.22 | 1.24 |
| 120926 | BRD-A18611368 | HEK293 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121024 | BRD-A18611368 | MCF??7.00 | 0.125 uM | 24 h | -0.2 | -0.83 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121084 | BRD-A18611368 | YAPC | 10 uM | 24 h | -0.27 | -1.12 | 0.38 | 0.31 | 1.08 | 0.66 |
| 129126 | BRD-A18611368 | HA1E | 0.25 uM | 24 h | 0.3 | 1.25 | 0.55 | 0.32 | 1.12 | 0.77 |
| 129158 | BRD-A18611368 | HELA | 2.22 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129175 | BRD-A18611368 | HT29 | 0.25 uM | 24 h | -0.23 | -0.97 | 0.11 | -0.24 | -0.82 | 0.15 |
| 129211 | BRD-A18611368 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.39 | 1.38 | 2.17 |