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CMap Candidate Details

Structure:
CMap ID: C05253
Pert ID: BRD-K45044657
Compound Name: TC-H-106
Targets: HDAC1|HDAC2|HDAC3|HDAC8
MoA: HDAC inhibitor
SMILES: Cc1ccc(NC(=O)CCCCCC(=O)Nc2ccccc2N)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29854 BRD-K45044657 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30063 BRD-K45044657 A549 10 uM 24 h -0.33 -1.37 1.08 0.0 0.0 0.0
30445 BRD-K45044657 ASC 10 uM 24 h 0.2 0.84 0.0 0.21 0.73 0.03
30752 BRD-K45044657 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31042 BRD-K45044657 HCC515 10 uM 6 h 0.22 0.9 0.02 -0.24 -0.8 0.12
31349 BRD-K45044657 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31520 BRD-K45044657 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31873 BRD-K45044657 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32179 BRD-K45044657 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32428 BRD-K45044657 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32777 BRD-K45044657 PC3 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.06 0.74
33027 BRD-K45044657 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33287 BRD-K45044657 VCAP 10 uM 24 h 0.22 0.91 0.03 0.28 1.01 0.44
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).