CMap Candidate Details
Structure:
| CMap ID: | C00526 |
| Pert ID: | BRD-K24593301 |
| Compound Name: | AZD3463 |
| Targets: | ALK|IGF1R |
| MoA: | ALK tyrosine kinase receptor inhibitor; insulin growth factor receptor inhibitor |
| SMILES: | COc1cc(ccc1Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12)N1CCC(N)CC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95481 | BRD-K24593301 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95597 | BRD-K24593301 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95692 | BRD-K24593301 | U2OS | 0.12 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96613 | BRD-K24593301 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96685 | BRD-K24593301 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.27 | 0.96 | 0.33 |