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CMap Candidate Details

Structure:
CMap ID: C05300
Pert ID: BRD-K06147391
Compound Name: telenzepine
Targets: CHRM1
MoA: acetylcholine receptor antagonist
SMILES: CN1CCN(CC(=O)N2c3c(C)scc3C(=O)Nc3ccccc23)CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2981 BRD-K06147391 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3329 BRD-K06147391 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.08
3717 BRD-K06147391 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.08
39088 BRD-K06147391 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39424 BRD-K06147391 A549 10 uM 6 h 0.27 1.13 0.29 0.0 0.0 0.0
39622 BRD-K06147391 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39943 BRD-K06147391 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40223 BRD-K06147391 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40746 BRD-K06147391 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41047 BRD-K06147391 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41374 BRD-K06147391 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51358 BRD-K06147391 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51419 BRD-K06147391 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91120 BRD-K06147391 HUH7 8 uM 72 h 0.0 0.0 0.0 -0.33 -1.1 0.86
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).