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CMap Candidate Details

Structure:
CMap ID: C05306
Pert ID: BRD-A93093700
Compound Name: temazepam
Targets: GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GABRR1|GABRR2|GABRR3|TSPO
MoA: benzodiazepine receptor agonist
SMILES: CN1c2ccc(Cl)cc2C(=NC(O)C1=O)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128374 BRD-A93093700 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128424 BRD-A93093700 HEK293 0.125 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
128496 BRD-A93093700 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128534 BRD-A93093700 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128627 BRD-A93093700 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128707 BRD-A93093700 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136168 BRD-A93093700 A375 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
136213 BRD-A93093700 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136254 BRD-A93093700 HELA 2.22 uM 24 h 0.32 1.34 0.89 0.0 0.0 0.0
136305 BRD-A93093700 MCF10A 0.25 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
136334 BRD-A93093700 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
136359 BRD-A93093700 PC3 0.03 uM 24 h -0.26 -1.08 0.3 -0.26 -0.87 0.22
136381 BRD-A93093700 YAPC 0.08 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).