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CMap Candidate Details

Structure:
CMap ID: C05310
Pert ID: BRD-K32107296
Compound Name: temozolomide
Targets: MGMT
MoA: DNA alkylating agent
SMILES: Cn1nnc2c(ncn2c1=O)C(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1326 BRD-K32107296 U2OS 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8932 BRD-K32107296 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9406 BRD-K32107296 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10773 BRD-K32107296 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.58
11468 BRD-K32107296 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.44 1.57 2.34
12031 BRD-K32107296 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.36 1.27 1.34
12302 BRD-K32107296 NOMO1 10 uM 6 h -0.2 -0.82 0.0 0.34 1.21 1.13
12776 BRD-K32107296 SW480 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.25
13256 BRD-K32107296 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13611 BRD-K32107296 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91217 BRD-K32107296 HUH7 15 uM 72 h 0.27 1.14 0.31 -0.2 -0.66 0.01
99025 BRD-K32107296 NEU 10 uM 6 h 0.18 0.74 0.0 -0.34 -1.15 1.08
99140 BRD-K32107296 NPC 10 uM 24 h 0.28 1.17 0.37 -0.41 -1.39 2.02
119881 BRD-K32107296 A549 0.01 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119894 BRD-K32107296 HCC515 0.002 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.15
119917 BRD-K32107296 PC3 0.01 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.24
121987 BRD-K32107296 HELA 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122063 BRD-K32107296 HUVEC 3.33 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
122147 BRD-K32107296 MDAMB231 10 uM 24 h 0.22 0.92 0.04 0.26 0.94 0.28
122200 BRD-K32107296 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130239 BRD-K32107296 HA1E 2.22 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
130263 BRD-K32107296 HEK293 2.22 uM 24 h -0.25 -1.05 0.24 0.0 0.0 0.0
130325 BRD-K32107296 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130364 BRD-K32107296 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130410 BRD-K32107296 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
130436 BRD-K32107296 MCF??7.00 0.08 uM 24 h 0.21 0.88 0.01 0.27 0.96 0.34
130531 BRD-K32107296 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).