CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05314
Pert ID:	BRD-K48068743
Compound Name:	teneligliptin
Targets:	DPP4
MoA:	dipeptidyl peptidase inhibitor
SMILES:	Cc1cc(N2CCN(CC2)[C@@H]2CN[C@@H](C2)C(=O)N2CCSC2)n(n1)-c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95318	BRD-K48068743	A549	10 uM	48 h	0.0	0.0	0.0	-0.36	-1.2	1.16
95400	BRD-K48068743	U2OS	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96357	BRD-K48068743	A375	3.33 uM	24 h	0.0	0.0	0.0	0.3	1.05	0.57
125751	BRD-K48068743	HUVEC	1.11 uM	24 h	0.24	0.99	0.09	0.33	1.16	0.9
125786	BRD-K48068743	JURKAT	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125949	BRD-K48068743	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133712	BRD-K48068743	HA1E	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133742	BRD-K48068743	HEK293	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133777	BRD-K48068743	HELA	0.01 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.38
133808	BRD-K48068743	HT29	0.08 uM	24 h	0.0	0.0	0.0	-0.28	-0.93	0.36
133867	BRD-K48068743	MCF10A	0.03 uM	24 h	0.0	0.0	0.0	-0.22	-0.74	0.05
133893	BRD-K48068743	MCF??7.00	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133925	BRD-K48068743	MDAMB231	0.01 uM	24 h	0.0	0.0	0.0	-0.26	-0.88	0.26
133954	BRD-K48068743	PC3	2.22 uM	24 h	-0.24	-1.02	0.17	0.0	0.0	0.0
133988	BRD-K48068743	THP1	0.08 uM	24 h	0.2	0.84	0.0	0.23	0.83	0.11

Summary