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CMap Candidate Details

Structure:
CMap ID: C05315
Pert ID: BRD-A87479750
Compound Name: tenidap
Targets: KCNJ4|PTGS1
MoA: cyclooxygenase inhibitor
SMILES: NC(=O)N1C(=O)C(C(=O)c2cccs2)c2cc(Cl)ccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1849 BRD-A87479750 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2606 BRD-A87479750 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39605 BRD-A87479750 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39925 BRD-A87479750 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40728 BRD-A87479750 NEU 10 uM 24 h -0.28 -1.18 0.51 0.0 0.0 0.0
41030 BRD-A87479750 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
41353 BRD-A87479750 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100373 BRD-A87479750 U2OS 10 uM 6 h 0.0 0.0 0.0 0.26 0.9 0.22
127721 BRD-A87479750 A375 3.33 uM 24 h 0.33 1.38 1.01 0.27 0.97 0.36
127763 BRD-A87479750 A549 3.33 uM 24 h 0.0 0.0 0.0 -0.3 -1.03 0.62
127837 BRD-A87479750 HEK293 10 uM 24 h -0.18 -0.74 0.0 0.0 0.0 0.0
127911 BRD-A87479750 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127967 BRD-A87479750 MCF10A 10 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
128017 BRD-A87479750 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
128061 BRD-A87479750 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
135516 BRD-A87479750 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135538 BRD-A87479750 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135593 BRD-A87479750 HT29 2.22 uM 24 h -0.23 -0.95 0.08 0.0 0.0 0.0
135630 BRD-A87479750 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.45
135709 BRD-A87479750 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).