CMap Candidate Details
Structure:
| CMap ID: | C05329 |
| Pert ID: | BRD-A22256192 |
| Compound Name: | terazosin |
| Targets: | ADRA1A|ADRA1B|ADRA1D|KCNH2|KCNH6|KCNH7 |
| MoA: | adrenergic receptor antagonist |
| SMILES: | COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 19209 | BRD-A22256192 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.65 | 0.01 |
| 19542 | BRD-A22256192 | HA1E | 10 uM | 6 h | 0.35 | 1.46 | 1.12 | 0.0 | 0.0 | 0.0 |
| 19862 | BRD-A22256192 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 20188 | BRD-A22256192 | HEPG2 | 10 uM | 6 h | 0.23 | 0.94 | 0.06 | -0.36 | -1.21 | 1.24 |
| 20525 | BRD-A22256192 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 21676 | BRD-A22256192 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24372 | BRD-A22256192 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25125 | BRD-A22256192 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.18 | -0.61 | 0.0 |
| 51557 | BRD-A22256192 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91496 | BRD-A22256192 | HUH7 | 8 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |