CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05330
Pert ID:	BRD-K68132782
Compound Name:	terbinafine
Targets:	SQLE
MoA:	fungal squalene epoxidase inhibitor
SMILES:	CN(C\C=C\C#CC(C)(C)C)Cc1cccc2ccccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
24600	BRD-K68132782	A549	10 uM	24 h	-0.2	-0.83	0.0	-0.29	-0.97	0.46
25527	BRD-K68132782	VCAP	10 uM	6 h	-0.24	-0.98	0.13	0.0	0.0	0.0
50395	BRD-K68132782	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
90935	BRD-K68132782	HUH7	12 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
126355	BRD-K68132782	A375	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126419	BRD-K68132782	HEK293	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126511	BRD-K68132782	MCF10A	3.33 uM	24 h	0.33	1.38	0.97	0.0	0.0	0.0
126569	BRD-K68132782	PC3	0.37 uM	24 h	0.28	1.15	0.34	0.0	0.0	0.0
126591	BRD-K68132782	YAPC	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134389	BRD-K68132782	HA1E	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134419	BRD-K68132782	HELA	0.01 uM	24 h	0.2	0.83	0.0	0.32	1.14	0.87
134449	BRD-K68132782	HT29	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134486	BRD-K68132782	HUVEC	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134559	BRD-K68132782	MCF??7.00	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134587	BRD-K68132782	MDAMB231	0.08 uM	24 h	0.0	0.0	0.0	-0.17	-0.58	0.0

Summary