CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05341
Pert ID:	BRD-A64228451
Compound Name:	terreic-acid-(-)
Targets:	BTK
MoA:	Bruton's tyrosine kinase (BTK) inhibitor
SMILES:	CC1C(=O)[C@H]2O[C@H]2C(=O)C1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
34001	BRD-A64228451	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
34278	BRD-A64228451	HA1E	10 uM	6 h	-0.25	-1.05	0.24	-0.45	-1.5	15.35
34514	BRD-A64228451	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
34784	BRD-A64228451	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35057	BRD-A64228451	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35491	BRD-A64228451	MCF??7.00	10 uM	6 h	-0.25	-1.06	0.26	0.0	0.0	0.0
36158	BRD-A64228451	PHH	10 uM	24 h	0.22	0.91	0.03	0.0	0.0	0.0
36453	BRD-A64228451	SKB	10 uM	24 h	0.0	0.0	0.0	-0.22	-0.73	0.04
36937	BRD-A64228451	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
96087	BRD-A64228451	A549	10 uM	24 h	-0.2	-0.85	0.01	0.0	0.0	0.0
96869	BRD-A64228451	A375	10 uM	24 h	0.25	1.05	0.17	-0.33	-1.1	0.87
96942	BRD-A64228451	PC3	10 uM	24 h	0.0	0.0	0.0	0.3	1.07	0.63
98977	BRD-A64228451	NEU	10 uM	6 h	0.22	0.92	0.04	-0.37	-1.26	1.36
99202	BRD-A64228451	NPC	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary