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CMap Candidate Details

Structure:
CMap ID: C05345
Pert ID: BRD-A55393291
Compound Name: testosterone
Targets: AR
MoA: androgen receptor agonist
SMILES: C[C@]12CCC3C(CCC4=CC(=O)CC[C@]34C)C1CC[C@@H]2O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5528 BRD-A55393291 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5845 BRD-A55393291 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6471 BRD-A55393291 VCAP 10 uM 6 h 0.23 0.96 0.08 -0.22 -0.74 0.06
37243 BRD-A55393291 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37518 BRD-A55393291 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38367 BRD-A55393291 NPC 10 uM 24 h 0.0 0.0 0.0 -0.47 -1.57 15.65
38648 BRD-A55393291 PHH 10 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
100226 BRD-A55393291 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
123578 BRD-A55393291 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123653 BRD-A55393291 HT29 0.04 uM 24 h -0.3 -1.26 0.71 0.0 0.0 0.0
123695 BRD-A55393291 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131986 BRD-A55393291 A375 0.74 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
132014 BRD-A55393291 HA1E 0.74 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
132040 BRD-A55393291 HELA 2.22 uM 24 h 0.21 0.88 0.02 -0.27 -0.9 0.29
132086 BRD-A55393291 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.84
132117 BRD-A55393291 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132142 BRD-A55393291 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).