CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05362
Pert ID:	BRD-A52660433
Compound Name:	tetrindole
Targets:	MAOA
MoA:	monoamine oxidase inhibitor
SMILES:	C1CCC(CC1)c1ccc2n3CCNC4CCCc(c34)c2c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
6842	BRD-A52660433	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
7085	BRD-A52660433	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
7237	BRD-A52660433	HA1E	10 uM	24 h	0.2	0.85	0.0	0.33	1.15	0.89
7555	BRD-A52660433	HCC515	10 uM	6 h	0.0	0.0	0.0	0.35	1.24	1.24
7955	BRD-A52660433	HT29	10 uM	6 h	-0.28	-1.15	0.44	0.0	0.0	0.0
8308	BRD-A52660433	PC3	10 uM	24 h	-0.22	-0.93	0.07	0.0	0.0	0.0
8588	BRD-A52660433	VCAP	10 uM	24 h	-0.29	-1.22	0.61	0.26	0.91	0.23
100209	BRD-A52660433	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
124345	BRD-A52660433	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124408	BRD-A52660433	JURKAT	1.11 uM	24 h	0.21	0.87	0.01	-0.38	-1.26	1.38
124447	BRD-A52660433	MCF10A	0.37 uM	24 h	-0.28	-1.16	0.46	0.0	0.0	0.0
124462	BRD-A52660433	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124539	BRD-A52660433	YAPC	10 uM	24 h	0.0	0.0	0.0	0.35	1.25	1.29
132416	BRD-A52660433	HEK293	0.01 uM	24 h	0.0	0.0	0.0	-0.3	-1.0	0.53
132546	BRD-A52660433	MDAMB231	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132596	BRD-A52660433	THP1	0.74 uM	24 h	-0.22	-0.92	0.06	-0.23	-0.77	0.08

Summary