CMap Candidate Details
Structure:
| CMap ID: | C05388 |
| Pert ID: | BRD-K26619122 |
| Compound Name: | thiocolchicoside |
| Targets: | GABRA1|GABRB2|GABRG2|GLRA1|GLRB |
| MoA: | GABA receptor antagonist |
| SMILES: | COc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc2CC[C@H](NC(C)=O)c3cc(=O)c(SC)ccc3-c2c1OC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 97159 | BRD-K26619122 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 97225 | BRD-K26619122 | PC3 | 10 uM | 24 h | 0.24 | 0.99 | 0.09 | -0.19 | -0.64 | 0.01 |
| 119977 | BRD-K26619122 | A549 | 0.125 uM | 24 h | 0.26 | 1.07 | 0.19 | 0.0 | 0.0 | 0.0 |
| 120093 | BRD-K26619122 | HT29 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120137 | BRD-K26619122 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.88 | 0.19 |
| 120210 | BRD-K26619122 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128807 | BRD-K26619122 | HA1E | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128825 | BRD-K26619122 | HELA | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.24 | 1.33 |
| 136403 | BRD-K26619122 | SHSY5Y | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.08 | 0.8 |