CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05396
Pert ID:	BRD-K08619574
Compound Name:	thioproperazine
Targets:	ADRA1A\|ADRA1B\|DRD1\|DRD2\|HTR1A\|HTR2A
MoA:	dopamine receptor antagonist
SMILES:	CN(C)S(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCN(C)CC3)c2c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4049	BRD-K08619574	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4351	BRD-K08619574	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5027	BRD-K08619574	VCAP	10 uM	6 h	0.27	1.11	0.25	-0.18	-0.6	0.0
44294	BRD-K08619574	A375	10 uM	6 h	0.0	0.0	0.0	-0.37	-1.26	1.36
44516	BRD-K08619574	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44843	BRD-K08619574	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45151	BRD-K08619574	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45418	BRD-K08619574	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45768	BRD-K08619574	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45957	BRD-K08619574	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46277	BRD-K08619574	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46592	BRD-K08619574	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
51427	BRD-K08619574	PC3	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.01	0.58

Summary