CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C05398
Pert ID:	BRD-A56012032
Compound Name:	thiorphan
Targets:	MME
MoA:	membrane metalloendopeptidase inhibitor
SMILES:	OC(=O)CNC(=O)C(CS)Cc1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5406	BRD-A56012032	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5530	BRD-A56012032	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5848	BRD-A56012032	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5984	BRD-A56012032	HT29	10 uM	6 h	0.25	1.03	0.13	-0.26	-0.86	0.22
6473	BRD-A56012032	VCAP	10 uM	6 h	0.0	0.0	0.0	0.23	0.82	0.1
44251	BRD-A56012032	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44485	BRD-A56012032	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44776	BRD-A56012032	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45746	BRD-A56012032	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45895	BRD-A56012032	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46212	BRD-A56012032	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46527	BRD-A56012032	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96520	BRD-A56012032	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.22	0.79	0.07

Summary