CMap Candidate Details
Structure:
| CMap ID: | C00054 |
| Pert ID: | BRD-A29260609 |
| Compound Name: | acebutolol |
| Targets: | ADRB1|ADRB2 |
| MoA: | adrenergic receptor antagonist |
| SMILES: | CCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(c1)C(C)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 50289 | BRD-A29260609 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50981 | BRD-A29260609 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51389 | BRD-A29260609 | PC3 | 10 uM | 24 h | 0.24 | 1.02 | 0.12 | 0.24 | 0.85 | 0.14 |
| 119953 | BRD-A29260609 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.75 | 0.07 |
| 119995 | BRD-A29260609 | A549 | 10 uM | 24 h | -0.34 | -1.4 | 1.15 | -0.24 | -0.81 | 0.13 |
| 120057 | BRD-A29260609 | HELA | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.82 | 0.14 |
| 120112 | BRD-A29260609 | HT29 | 10 uM | 24 h | -0.18 | -0.74 | 0.0 | 0.36 | 1.26 | 1.29 |
| 120154 | BRD-A29260609 | MCF??7.00 | 0.125 uM | 24 h | -0.3 | -1.24 | 0.64 | 0.31 | 1.09 | 0.67 |
| 128816 | BRD-A29260609 | HA1E | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128877 | BRD-A29260609 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |