CMap Candidate Details
Structure:
| CMap ID: | C05414 |
| Pert ID: | BRD-A53077924 |
| Compound Name: | tianeptine |
| Targets: | OPRD1|OPRK1|OPRM1 |
| MoA: | selective serotonin reuptake enhancer (SSRE) |
| SMILES: | CN1c2ccccc2C(NCCCCCCC(O)=O)c2ccc(Cl)cc2S1(=O)=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1442 | BRD-A53077924 | NPC | 8 uM | 24 h | -0.24 | -0.99 | 0.13 | 0.0 | 0.0 | 0.0 |
| 6843 | BRD-A53077924 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7086 | BRD-A53077924 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.23 | 0.82 | 0.1 |
| 7238 | BRD-A53077924 | HA1E | 10 uM | 24 h | 0.2 | 0.82 | 0.0 | -0.24 | -0.81 | 0.13 |
| 7556 | BRD-A53077924 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7956 | BRD-A53077924 | HT29 | 10 uM | 6 h | -0.29 | -1.2 | 0.57 | 0.0 | 0.0 | 0.0 |
| 8245 | BRD-A53077924 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.31 | 1.71 |
| 8454 | BRD-A53077924 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8589 | BRD-A53077924 | VCAP | 10 uM | 24 h | 0.28 | 1.16 | 0.34 | 0.0 | 0.0 | 0.0 |
| 100212 | BRD-A53077924 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.71 | 0.04 |